She is of Chinese-Vietnamese descent and grew up in Quincy, Massachusetts.
In 2010, Chan and Zuckerberg signed the "Giving Pledge," promising to donate the majority of their wealth to philanthropic causes.
In 2012, Chan and Zuckerberg announced the formation of the Chan Zuckerberg Initiative.
She met her husband, Facebook co-founder Mark Zuckerberg, while they were both attending Harvard.
Chan serves as the CEO of the Chan Zuckerberg Initiative and has been actively involved in its various initiatives and partnerships.
She is also a pediatrician and has worked at San Francisco General Hospital and the University of California, San Francisco.
Chan is passionate about education and has been involved in various education-related initiatives, including serving on the board of The Primary School .
In addition to her philanthropic work, Chan is an avid cook and enjoys sharing her recipes and cooking tips on her Instagram account.